Synthesis and Study of Acridine Derivatives as Potential Chemotherapeutic agents
Acridine dyes are commonly used for DNA-drug interaction studies because their polycyclic, planar, and aromatic structures can intercalate between adjacent DNA bases, stopping transcription and serving as potential chemotherapeutic agents. In my research, I have prepared a number of acridine derivatives to understand DNA-ligand interactions and structure-activity relationships better.